Revolutionizing Cardiovascular Regeneration
Welcome to Yoon Lab, a pioneering center for regenerative medicine focused on combating cardiovascular diseases. At the heart of our mission is the development of innovative strategies that leverage the power of stem cells and tissue engineering technologies.
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Diverse Stem Cell Applications
Our research delves into the use of both pluripotent and adult stem cells for heart and vascular regeneration. We focus on pluripotent cells like induced pluripotent and embryonic stem cells for their adaptability. Simultaneously, we tap into the potential of adult stem cells, including endothelial, mesenchymal, and bone marrow-derived multipotent stem cells, along with CD31+ and hematopoietic stem cells, for their targeted repair capabilities.
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Cardiovascular Disease Intervention
Our efforts are directed towards tackling key cardiovascular diseases, including myocardial infarction, chronic heart failure, peripheral vascular diseases like peripheral arterial occlusive disease, diabetic neuropathy, lymphedema, and wound healing. By understanding and addressing these conditions, we aim to bring forward new therapeutic approaches and improve patient outcomes.
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In Vitro Differentiation Innovation
We are at the forefront of innovating with in vitro differentiation of pluripotent stem cells. Our focus is on transforming these cells into endothelial cells, cardiomyocytes, and lymphatic vessels, exploring their potential in effectively treating targeted cardiovascular diseases. This approach opens new avenues for understanding disease mechanisms and developing tailored therapies.
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Biomaterial-Enhanced Stem Cell Therapy
A pioneering aspect of our research involves integrating biomaterial technologies with stem cell applications. This synergy enhances cardiac repair, offering a novel approach to healing heart tissue. Through this integration, we aim to improve the efficacy and durability of stem cell therapies in cardiac regeneration, marking a significant advancement in cardiac care.
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The Mission of Yoon Lab

Our expertise lies in the generation and manipulation of various stem and progenitor cells, including induced pluripotent stem cells, multipotent bone marrow cells, and angio-vasculogenic cells. By harnessing the potential of these cells, we aim to create effective therapies for a range of cardiovascular conditions. Our primary focus is on differentiating these cells into specialized types, such as endothelial cells and cardiomyocytes, to repair and regenerate damaged heart and blood vessels.

Our research is particularly relevant in addressing peripheral vascular disease and its complications in diabetes, myocardial infarction, lymphedema, and diabetic neuropathy. By delving deep into the mechanistic aspects of these diseases, we strive to understand and enhance the therapeutic utility of our cellular and tissue engineering approaches.

At Yoon Lab, we are committed to advancing the frontiers of medicine through our dedicated research, innovative strategies, and the relentless pursuit of knowledge to improve patient outcomes in cardiovascular diseases. Join us in our journey towards a healthier, heartier future.

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News and Updates

Regenerative Medicine at Emory University

Researchers in Emory University’s new regenerative medicine program are working to develop new therapies for cardiovascular disease. Emory Department of Medicine Vice Chair and Cardiology Division Director W. Robert Taylor, MD, PhD; Rebecca Levit, MD; and Young-sup Yoon, MD, PhD discuss the regenerative medicine program at Emory University School of Medicine.